The antibiotic tightrope

Escalating antibiotic resistance (AMR) in severe infection forces clinicians to walk a tightrope that balances unnecessary antibiotic use with diagnostic test-targeted prescribing. Better diagnostic tests will help find that balance.

That soprano again

Septicaemia is a complex clinical entity. Successful clinical management requires prompt decision-making supported by selective use of laboratory aids. A knowledge of the local epidemiology assists presumptive antibiotic choice.